基因名:
TERF2
产品别名:
TRBF2; TRF2; TERF2; telomeric repeat binding factor 2; telomeric repeat binding factor 2; telomeric repeat-binding factor 2; TTAGGG repeat-binding factor 2; telomeric DNA-binding protein; telomeric repeat binding protein 2; 端粒结合蛋白2; 端粒重复结合因子2(TERF2);
背景信息:
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008]