基因名:
TGFB2
产品别名:
G-TSF; LDS4; TGF-beta2; TGFB2; transforming growth factor beta 2; transforming growth factor beta 2; transforming growth factor beta-2 proprotein; BSC-1 cell growth inhibitor; cetermin; glioblastoma-derived T-cell suppressor factor; polyergin; prepro-transforming growth factor beta-2; TGF beta 2蛋白; 转化生长因子β2(TGFb2); 转化生长因子β2(TGFβ2); 转移生长因子β2;
背景信息:
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).