基因名:
TGM1
产品别名:
ARCI1; ICR2; KTG; LI; LI1; TGASE; TGK; TGM1; transglutaminase 1; transglutaminase 1; protein-glutamine gamma-glutamyltransferase K; K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase; TG(K); TGase K; TGase-1; epidermal TGase; transglutaminase K; transglutaminase, keratinocyte; 谷氨酰胺转胺酶1; 谷氨酰胺转胺酶1(TGM1);
背景信息:
Tissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is a relatively common disorder in Western countries.