基因名：
TIMP1
产品别名：
CLGI； EPA； EPO； HCI； TIMP； TIMP-1； TIMP1； TIMP metallopeptidase inhibitor 1； TIMP metallopeptidase inhibitor 1； metalloproteinase inhibitor 1； collagenase inhibitor； epididymis secretory sperm binding protein； erythroid potentiating activity； fibroblast collagenase inhibitor； tissue inhibitor of metalloproteinases 1； 组织金属蛋白酶抑制因子1(TIMP1)； 组织金属蛋白酶抑制因子1(TIMP1)真核蛋白； 金属蛋白酶组织抑制因子-1； 金属蛋白酶组织抑制因子-1蛋白；
背景信息：
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
