基因名:
TIMP3
产品别名:
HSMRK222; K222; K222TA2; SFD; TIMP3; TIMP metallopeptidase inhibitor 3; TIMP metallopeptidase inhibitor 3; metalloproteinase inhibitor 3; MIG-5 protein; TIMP-3; protein MIG-5; tissue inhibitor of metalloproteinases 3; 组织金属蛋白酶抑制因子3(TIMP3); 金属蛋白酶组织抑制因子-3;
背景信息:
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008].