基因名:
UBP1
产品别名:
LBP-1B; LBP-1a; LBP1A; LBP1B; UBP1; upstream binding protein 1; upstream binding protein 1; upstream-binding protein 1; transcription factor LBP-1; 上游结合蛋白1;
背景信息:
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.