基因名：
UCHL3
产品别名：
UCH-L3； UCHL3； ubiquitin C-terminal hydrolase L3； ubiquitin C-terminal hydrolase L3； ubiquitin carboxyl-terminal hydrolase isozyme L3； testicular tissue protein Li 221； ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)； ubiquitin thioesterase L3； ubiquitin thiolesterase； 泛素硫酯酶L3； 泛素羧基端酯酶L3(UCHL3)；
背景信息：
Ubiquitin Carboxyl-Terminal Hydrolases (UCHs) are a family of cysteine hydrolases. They catalyze the hydrolysis of amides, thioesters and esters, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin. Up regulation of UCHL3 is associated with uterine cervical neoplasms. UCHL3 is implicated in age related cognitive disorders. UCHL3 also promotes adipogenesis and insulin signaling. In mice, UCHL3 knockout have been shown to be resistant to diet-induced obesity.
