基因名:
UCP2
产品别名:
BMIQ4; SLC25A8; UCPH; UCP2; uncoupling protein 2; uncoupling protein 2; mitochondrial uncoupling protein 2; solute carrier family 25 member 8; uncoupling protein 2 (mitochondrial, proton carrier); 线粒体脱偶连蛋白2; 解偶联蛋白2(UCP2);
背景信息:
UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.