基因名：
NR1H2
产品别名：
LXR-b； LXRB； NER； NER-I； RIP15； UNR； NR1H2； nuclear receptor subfamily 1 group H member 2； nuclear receptor subfamily 1 group H member 2； oxysterols receptor LXR-beta； LX receptor beta； liver X nuclear receptor beta； nuclear orphan receptor LXR-beta； nuclear receptor NER； steroid hormone-nuclear receptor NER； ubiquitously-expressed nuclear receptor； 肝X受体β(LXRb)； 肝脏X受体β；
背景信息：
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
