基因名:
USF1
产品别名:
FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; bHLHb11; USF1; upstream transcription factor 1; upstream transcription factor 1; upstream stimulatory factor 1; class B basic helix-loop-helix protein 11; major late transcription factor 1; 等上游刺激因子1;
背景信息:
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene. Alternate Names: upstream stimulatory factor 1; transcription factor USF-1; bHLHb11; Upstream stimulatory factor 1; Major late transcription factor 1.