基因名：
TRPV1
产品别名：
VR1； TRPV1； transient receptor potential cation channel subfamily V member 1； transient receptor potential cation channel subfamily V member 1； transient receptor potential cation channel subfamily V member 1； OTRPC1； capsaicin receptor； osm-9-like TRP channel 1； transient receptor potential vanilloid 1a； transient receptor potential vanilloid 1b； vanilloid receptor subtype 1； 转化受体电位阳离子通道亚家族V成员1(TRPV1)； 辣椒素受体；
背景信息：
The detection of noxious stimuli (chemical, mechanical, or thermal) occurs predominantly at the peripheral terminals of primary afferent neurons. This information is ultimately transmitted to the central nervous system to evoke a perception of pain which initiates appropriate protective reflexes. The receptor for capsaicin, VR1 (vanilloid receptor 1; TRPV1 is a nonselective cation channel that resembles members of the transient receptor potential (TRP) family of ion channels. The vanilloid receptor 1 protein functions both as a receptor for capsaicin and a transducter of noxious thermal stimuli. VR1 protein is localized to small-diameter sensory neurons within the dorsal root ganglia and nerve terminals in the dorsal horn.
