基因名:
WEE1
产品别名:
WEE1A; WEE1hu; WEE1; WEE1 G2 checkpoint kinase; WEE1 G2 checkpoint kinase; wee1-like protein kinase; WEE1 homolog; WEE1+ homolog; protein kinase; wee1A kinase; WEE1蛋白; 磷酸化WEE1蛋白;
背景信息:
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.