基因名:
XPO1
产品别名:
CRM-1; CRM1; emb; exp1; XPO1; exportin 1; exportin 1; exportin-1; chromosome region maintenance 1 homolog; chromosome region maintenance 1 protein homolog; exportin 1 (CRM1 homolog, yeast); exportin-1 (required for chromosome region maintenance); 染色体区域稳定蛋白/核输出蛋白1; 染色体区域稳定蛋白/核输出蛋白1/染色体区域稳定必需蛋白; 输出蛋白1(XPO1);
背景信息:
The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jul 2008]