基因名：
ZIC2
产品别名：
HPE5； ZIC2； Zic family member 2； Zic family member 2； zinc finger protein ZIC 2； Zic family member 2 (odd-paired homolog, Drosophila)； Zinc finger protein of the cerebellum 2； 锌指蛋白Zic2；
背景信息：
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2008]
