基因名：
TFPI2
产品别名：
PP5； REF1； TFPI-2； TFPI2； tissue factor pathway inhibitor 2； tissue factor pathway inhibitor 2； tissue factor pathway inhibitor 2； placental protein 5； retinal pigment epithelium cell factor 1； 组织因子途径抑制剂-2； 组织因子通道抑制因子2(TFPI2)；
背景信息：
Human Tissue Factor Pathway Inhibitor 2 (TFPI2) has a N-terminal acidic region, three Kunita domains separated with by two linker regions, and a C-terminal basic region. TFPI2 has the function of regulating plasmin-mediated matrix remodeling, inhibits trypsin, plasmin, factor Vlla/tissue factor and weakly factor Xa.. TFPI2 has no effect on thrombin. TFPI2 may contribute to tumor progression in many cancers; in these cancers, the expression of TFPI2 can be down-regulated.
