基因名：
PTP4A2
产品别名：
HH13； HH7-2； HU-PP-1； OV-1； PRL-2； PRL2； PTP4A； PTPCAAX2； ptp-IV1a； ptp-IV1b； PTP4A2； protein tyrosine phosphatase 4A2； protein tyrosine phosphatase 4A2； protein tyrosine phosphatase type IVA 2； PTP(CAAXII)； phosphatase of regenerating liver 2； protein tyrosine phosphatase IVA； protein tyrosine phosphatase IVA2； protein tyrosine phosphatase type IVA, member 2； protein-tyrosine phosphatase of regenerating liver 2； 肝再生磷酸酯酶2； 蛋白酪氨酸磷酸酶ⅣA2(PTP4A2)；
背景信息：
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
