基因名:
TAF15
产品别名:
Npl3; RBP56; TAF2N; TAFII68; TAF15; TATA-box binding protein associated factor 15; TATA-box binding protein associated factor 15; TATA-binding protein-associated factor 2N; RBP56/CSMF fusion; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56); TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TBP-associated factor 15; RNA结合蛋白56;
背景信息:
This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]