基因名:
CHAF1B
产品别名:
CAF-1; CAF-IP60; CAF1; CAF1A; CAF1P60; MPHOSPH7; MPP7; CHAF1B; chromatin assembly factor 1 subunit B; chromatin assembly factor 1 subunit B; chromatin assembly factor 1 subunit B; CAF-1 subunit B; CAF-I 60 kDa subunit; CAF-I p60; M-phase phosphoprotein 7; chromatin assembly factor I p60 subunit; human chromatin assembly factor-I p60 subunit; 染色质组装因子1P60; 染色质装配因子1亚基B(CHAF1B);
背景信息:
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]