基因名:
USP11
产品别名:
UHX1; USP11; ubiquitin specific peptidase 11; ubiquitin specific peptidase 11; ubiquitin carboxyl-terminal hydrolase 11; deubiquitinating enzyme 11; ubiquitin carboxyl-terminal hydrolase, X-linked; ubiquitin thioesterase 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11;
背景信息:
Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. Usp11 belongs to the ubiquitin-specific protease family. It helps in repairing DNA damage. It has been found to interact with RanBPM, a RanGTP-binding protein.