基因名:
SORBS2
产品别名:
ARGBP2; PRO0618; SORBS2; sorbin and SH3 domain containing 2; sorbin and SH3 domain containing 2; sorbin and SH3 domain-containing protein 2; Arg binding protein 2; Arg/Abl-interacting protein 2; arg-binding protein 2; 精氨酸结合蛋白2;
背景信息:
SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form a complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.