基因名:
CDC14B
产品别名:
CDC14B3; Cdc14B1; Cdc14B2; hCDC14B; CDC14B; cell division cycle 14B; cell division cycle 14B; dual specificity protein phosphatase CDC14B; CDC14 cell division cycle 14 homolog B; 细胞分裂周期蛋白14B;
背景信息:
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].