基因名:
TMEFF1
产品别名:
C9orf2; CT120.1; H7365; TR-1; TMEFF1; transmembrane protein with EGF like and two follistatin like domains 1; transmembrane protein with EGF like and two follistatin like domains 1; tomoregulin-1; cancer/testis antigen family 120, member 1; transmembrane protein with EGF-like and one follistatin-like domain; TEFF1蛋白; 肿瘤调节蛋白1(TR1); 脑肿瘤抑癌蛋白1;
背景信息:
Tomoregulin-1 precursor is a single-pass type I membrane protein thought to be a tumor suppressor in brain cancers. Its expression is down-regulated in these tumors as compared to control brain tissues. In addition, it might also inhibit NODAL and BMP signaling during neural patterning. There are 2 isoforms produced by alternative splicing.