基因名:
NCOA1
产品别名:
F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74; NCOA1; nuclear receptor coactivator 1; nuclear receptor coactivator 1; nuclear receptor coactivator 1; Hin-2 protein; class E basic helix-loop-helix protein 74; renal carcinoma antigen NY-REN-52; steroid receptor coactivator-1; 核受体共激活剂1; 核受体共激活因子1(NCOA1);
背景信息:
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]