重组细胞因子信号传导抑制蛋白1

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重组细胞因子信号传导抑制蛋白1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组细胞因子信号转导抑制因子1(SOCS1)蛋白
Recombinant SOCS1

基因名：

SOCS1

产品别名：

AISIMD； CIS1； CISH1； JAB； SOCS-1； SSI-1； SSI1； TIP-3； TIP3； SOCS1； suppressor of cytokine signaling 1； suppressor of cytokine signaling 1； suppressor of cytokine signaling 1； JAK binding protein； STAT induced SH3 protein 1； STAT-induced STAT inhibitor 1； Tec-interacting protein 3； cytokine-inducible SH2 protein 1；细胞因子信号传导抑制蛋白1；细胞因子信号转导抑制因子1(SOCS1)；

背景信息：

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity (By similarity). Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor(LIF). Regulates interferon-gamma mediated sensory neuron survival. Implicated, through SOCS box binding, in ubiquitin-dependent protein degradation. High expression in thymus. Lower expression in lung and spleen.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。