基因名:
CDC23
产品别名:
ANAPC8; APC8; CUT23; CDC23; cell division cycle 23; cell division cycle 23; cell division cycle protein 23 homolog; anaphase-promoting complex subunit 8; cell division cycle 23 homolog; cyclosome subunit 8; 细胞分裂周期因子23(CDC23); 细胞分裂周期蛋白23;
背景信息:
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]