基因名:
TRADD
产品别名:
Hs.89862; TRADD; TNFRSF1A associated via death domain; TNFRSF1A associated via death domain; tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated death domain protein; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor-1-associated protein; TNFRSF1A关联Via死亡域蛋白(TRADD); 肿瘤坏死因子受体1相关死亡域蛋白;
背景信息:
Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.