重组凋亡诱导受体TNFRSF25蛋白

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重组凋亡诱导受体TNFRSF25蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组死亡受体3蛋白
Recombinant TNFRSF25

基因名：

TNFRSF25

产品别名：

APO-3； DDR3； DR3； GEF720； LARD； PLEKHG5； TNFRSF12； TR3； TRAMP； WSL-1； WSL-LR； TNFRSF25； TNF receptor superfamily member 25； TNF receptor superfamily member 25； tumor necrosis factor receptor superfamily member 25； Guanine nucleotide exchange factor 720； PH domain-containing family G member 5； Pleckstrin homology domain-containing family G member 5； apoptosis inducing receptor； apoptosis-inducing receptor AIR； apoptosis-mediating receptor DR3； apoptosis-mediating receptor TRAMP； death domain receptor 3 soluble form； death receptor beta； lymphocyte-associated receptor of death； protein WSL-1； tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)；凋亡诱导受体TNFRSF25；死亡受体3；肿瘤坏死因子受体超家族成员25(TNFRSF25)；

背景信息：

Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) contains 1 death domain and 4 TNFR-Cys repeats. TNFRSF25 is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation, activated by a monogamous ligand, known as TL1A (TNFSF15), which is rapidly upregulated in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal both through the TRADD adaptor molecule to stimulate NF-kappa B activity or through the FADD adaptor molecule to stimulate caspase activation and regulate cell apoptosis. It may play a role in regulating lymphocyte homeostasis.