基因名:
TRIM24
产品别名:
PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA; hTIF1; TRIM24; tripartite motif containing 24; tripartite motif containing 24; transcription intermediary factor 1-alpha; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; TIF1-alpha; transcriptional intermediary factor 1; 转录中介因子Tif1α;
背景信息:
TIF1 alpha mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains (a RING, a B box type 1 and a B box type 2) and a coiled coil region.