重组磷酸化认知缺陷突触相关蛋白SynGAP

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重组突触Ras GTP酶激活蛋白1(SYNGAP1)
Recombinant SYNGAP1

基因名：

SYNGAP1

产品别名：

MRD5； RASA1； RASA5； SYNGAP； SYNGAP1； synaptic Ras GTPase activating protein 1； synaptic Ras GTPase activating protein 1； ras/Rap GTPase-activating protein SynGAP； Ras GTPase-activating protein SynGAP； neuronal RasGAP； synaptic Ras GTPase activating protein 1 homolog； synaptic Ras GTPase activating protein, 135kDa；磷酸化认知缺陷突触相关蛋白SynGAP；突触Ras GTP酶激活蛋白1(SYNGAP1)；

背景信息：

The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。