重组孕烷X受体(PXR)蛋白

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重组孕烷X受体(PXR)蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组孤儿核受体PAR1蛋白
Recombinant NR1I2

基因名：

NR1I2

产品别名：

BXR； ONR1； PAR； PAR1； PAR2； PARq； PRR； PXR； SAR； SXR； NR1I2； nuclear receptor subfamily 1 group I member 2； nuclear receptor subfamily 1 group I member 2； nuclear receptor subfamily 1 group I member 2； orphan nuclear receptor PAR1； orphan nuclear receptor PXR； pregnane X receptor； steroid and xenobiotic receptor；孕烷X受体(PXR)；孤儿核受体PAR1；

背景信息：

The human nuclear pregnane X receptor (PXR) activates cytochrome P450-3A expression in response to a wide variety of xenobiotics and plays a critical role in mediating dangerous drug-drug interactions. The human PXR is related to the mouse Pxr1, which they had cloned and shown to be activated by dexamethasone, pregnenolone 16-alpha-carbonitrile (PCN), and other compounds known to induce expression of the CYP3A1 gene, the predominant form of CYP3A in rat liver and intestine. Northern blot analysis detected most abundant expression in liver, colon, and small intestine; transcripts of 2.6, 4.3, and 5 kb were present in each of these tissues.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。