基因名:
CDC16
产品别名:
ANAPC6; APC6; CDC16Hs; CUT9; CDC16; cell division cycle 16; cell division cycle 16; cell division cycle protein 16 homolog; anaphase-promoting complex, subunit 6; cell division cycle 16 homolog; cyclosome subunit 6; 磷酸化细胞分裂周期蛋白16; 细胞分裂周期因子16(CDC16); 细胞分裂周期蛋白16;
背景信息:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.