基因名:
ZPR1
产品别名:
GKAF; ZNF259; ZPR1; ZPR1 zinc finger; ZPR1 zinc finger; zinc finger protein ZPR1; zinc finger protein 259; 锌指蛋白259;
背景信息:
ZPR1 is a zinc finger-containing protein that is capable of binding to the intracellular tyrosine kinase domain of the epidermal growth factor receptor. Stimulation of mammalian cells with epidermal growth factor reduces ZPR1 affinity for the EGFR and leads to an accumulation of the protein in the nucleus. The ZPR1 zinc finger is necessary for its association with the EGFR.