基因名:
WASL
产品别名:
N-WASP; NWASP; WASPB; WASL; WASP like actin nucleation promoting factor; WASP like actin nucleation promoting factor; neural Wiskott-Aldrich syndrome protein; Wiskott-Aldrich syndrome like; 磷酸化神经Wiskott Aldrich综合征蛋白; 神经Wiskott Aldrich综合征蛋白;
背景信息:
This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013]