基因名:
SLC16A3
产品别名:
MCT 3; MCT 4; MCT-3; MCT-4; MCT3; MCT4; SLC16A3; solute carrier family 16 member 3; solute carrier family 16 member 3; monocarboxylate transporter 4; monocarboxylate transporter 3; solute carrier family 16 (monocarboxylate transporter), member 3; solute carrier family 16 (monocarboxylic acid transporters), member 3; solute carrier family 16, member 3 (monocarboxylic acid transporter 4); 单羧酸转运蛋4; 溶质载体家族16成员3(SLC16A3);
背景信息:
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]