基因名:
SMC3
产品别名:
BAM; BMH; CDLS3; CSPG6; HCAP; SMC3L1; SMC3; structural maintenance of chromosomes 3; structural maintenance of chromosomes 3; structural maintenance of chromosomes protein 3; SMC protein 3; basement membrane-associated chondroitin proteoglycan; chondroitin sulfate proteoglycan 6 (bamacan); chromosome-associated polypeptide; 基底膜相关软骨素蛋白多糖; 染色体结构维持蛋白3(SMC3); 磷酸化基底膜相关软骨素蛋白多糖;
背景信息:
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq].