基因名：
CBFA2T2
产品别名：
EHT； MTGR1； ZMYND3； p85； CBFA2T2； CBFA2/RUNX1 partner transcriptional co-repressor 2； CBFA2/RUNX1 partner transcriptional co-repressor 2； protein CBFA2T2； CBFA2/RUNX1 translocation partner 2； ETO homolog on chromosome 20； ETO homologous on chromosome 20； MTG8-like protein； MTG8-related protein 1； core-binding factor, runt domain, alpha subunit 2; translocated to, 2； myeloid translocation gene-related protein 1； myeloid translocation-related protein 1； 髓易位基因相关蛋白1；
背景信息：
May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
Tissue specificity:
Ubiquitously expressed in fetal and adult tissues. Highly expressed in adult brain, heart, lung, kidney, lymph node, appendix, thymus, testis, uterus, small intestine, prostate and thymus.
