基因名：
VAPB
产品别名：
ALS8； VAMP-B； VAP-B； VAPB； VAMP associated protein B and C； VAMP associated protein B and C； vesicle-associated membrane protein-associated protein B/C； VAMP (vesicle-associated membrane protein)-associated protein B and C； VAMP-associated 33 kDa protein； 囊泡关联膜蛋白关联蛋白B(VAPB)； 囊泡相关膜蛋白相关的蛋白B；
背景信息：
vesicle-associated membrane protein-associated protein B/C (VAPB) is presents in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. It can form homodimer, and heterodimer with VAPA. It also interacts with VAMP1, VAMP2, HCV NS5A, NS5B, ZFYVE27 and RMDN3. VAPB participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. It is involved in cellular calcium homeostasis regulation.
