基因名:
HMGN3
产品别名:
PNAS-24; PNAS-25; TRIP7; HMGN3; high mobility group nucleosomal binding domain 3; high mobility group nucleosomal binding domain 3; high mobility group nucleosome-binding domain-containing protein 3; TR-interacting protein 7; thyroid hormone receptor interacting protein 7; 高迁移率族核小体结合域蛋白3(HMGN3); 高迁移率族蛋白N3;
背景信息:
Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]