基因名：
EFTUD2
产品别名：
MFDGA； MFDM； SNRNP116； Snrp116； Snu114； U5-116KD； EFTUD2； elongation factor Tu GTP binding domain containing 2； elongation factor Tu GTP binding domain containing 2； 116 kDa U5 small nuclear ribonucleoprotein component； SNU114 homolog； U5 snRNP-specific protein, 116 kDa； elongation factor Tu GTP-binding domain-containing protein 2； hSNU114； 延伸因子结合蛋白EFTUD2；
背景信息：
Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA. Snrp116, also known as EFTUD2 (elongation factor Tu GTP binding domain containing 2) or Snu114, is a 972 amino acid protein that localizes to the nucleus and belongs to the GTP-binding elongation factor family. Existing as a component of the multi-protein U5 snRNP spliceosome complex, Snrp116 plays an important role in pre-mRNA splicing, as well as in the recycling of spliceosomal snRNPs. The gene encoding Snrp116 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
