基因名:
PPIG
产品别名:
CARS-Cyp; CYP; SCAF10; SRCyp; PPIG; peptidylprolyl isomerase G; peptidylprolyl isomerase G; peptidyl-prolyl cis-trans isomerase G; CARS-cyclophilin; CASP10; Clk-associating RS-cyclophilin; PPIase G; SR-cyclophilin; SR-cyp; SR-related CTD-associated factor 10; cyclophilin G; peptidyl-prolyl isomerase G (cyclophilin G); rotamase G; 亲环蛋白(亲环素)PPIG; 磷酸化亲环蛋白(亲环素)PPIG;
背景信息:
PPIG belongs to the the peptidyl-prolyl cis/trans isomerase protein family (PPIases). PPIases accelerate the folding of proteins. PPIG catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and is implicated in the folding, transport, and assembly of proteins. It is distributed in nuclear speckles, a nuclear compartment rich in splicing factors, and colocalizes with the splicing factors SC35 and pinin, suggesting a role in the regulation of pre-mRNA splicing.