重组磷酸化丝裂原活化蛋白激酶MAP4K4

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Recombinant MAP4K4
Recombinant mitogen-activated protein kinase kinase kinase kinase 4 protein

基因名：

MAP4K4

产品别名：

FLH21957； HEL-S-31； HGK； MEKKK4； NIK； MAP4K4； mitogen-activated protein kinase kinase kinase kinase 4； mitogen-activated protein kinase kinase kinase kinase 4； mitogen-activated protein kinase kinase kinase kinase 4； HPK/GCK-like kinase HGK； MAPK/ERK kinase kinase kinase 4； MEK kinase kinase 4； Ste20 group protein kinase HGK； epididymis secretory protein Li 31； hepatocyte progenitor kinase-like/germinal center kinase-like kinase； nck-interacting kinase；磷酸化丝裂原活化蛋白激酶MAP4K4；

背景信息：

MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.