基因名:
GGPS1
产品别名:
GGPPS; GGPPS1; MDHLO; MUDHLOV; GGPS1; geranylgeranyl diphosphate synthase 1; geranylgeranyl diphosphate synthase 1; geranylgeranyl pyrophosphate synthase; (2E,6E)-farnesyl diphosphate synthase; GGPP synthase; GGPPSase; dimethylallyltranstransferase; farnesyl diphosphate synthase; farnesyltranstransferase; geranyltranstransferase; 异戊二烯基二磷酸合酶1(GGPS1); 法尼基二磷酸合酶1;
背景信息:
Geranylgeranyl pyrophosphate synthase (GGPS1) is a member of the FPP/GGPP synthase family. GGPS1 is highly expressed in testis, heart and skeletal muscle. GGPS1 is localized in the cytoplasm and has geranylgeranyl diphosphate (GGPP) synthase activity. It catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. Other transcriptional splice variants have been found.