基因名：
SPTLC2
产品别名：
HSN1C； LCB2； LCB2A； NSAN1C； SPT2； hLCB2a； SPTLC2； serine palmitoyltransferase long chain base subunit 2； serine palmitoyltransferase long chain base subunit 2； serine palmitoyltransferase 2； LCB 2； SPT 2； long chain base biosynthesis protein 2a； serine palmitoyltransferase, subunit II； serine-palmitoyl-CoA transferase 2； 丝氨酸棕榈酰转移酶2； 丝氨酸棕榈酰转移酶长链碱性亚基2(SPTLC2)；
背景信息：
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
