基因名：
BAG2
产品别名：
BAG-2； dJ417I1.2； BAG2； BAG cochaperone 2； BAG cochaperone 2； BAG family molecular chaperone regulator 2； BCL2 associated athanogene 2； bcl-2-associated athanogene 2； dJ417I1.2 (BAG-family molecular chaperone regulator 2)； Bcl-2结合抑凋亡蛋白2； Bcl2关联永生基因2(BAG2)；
背景信息：
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
