基因名：
MINPP1
产品别名：
HIPER1； MINPP2； MIPP； PCH16； MINPP1； multiple inositol-polyphosphate phosphatase 1； multiple inositol-polyphosphate phosphatase 1； multiple inositol polyphosphate phosphatase 1； 2,3-BPG phosphatase； 2,3-bisphosphoglycerate 3-phosphatase； inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase； ins(1,3,4,5)P(4) 3-phosphatase； multiple inositol polyphosphate histidine phosphatase, 1； multiple inositol polyphosphate phosphatase 2； 多聚磷酸肌醇磷酸酶1；
背景信息：
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
