基因名：
CELSR1
产品别名：
ADGRC1； CDHF9； FMI2； HFMI2； LMPHM9； ME2； CELSR1； cadherin EGF LAG seven-pass G-type receptor 1； cadherin EGF LAG seven-pass G-type receptor 1； cadherin EGF LAG seven-pass G-type receptor 1； adhesion G protein-coupled receptor C1； cadherin family member 9； cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)； flamingo homolog 2； protocadherin flamingo 2； 钙粘蛋白EGF LAG七经G-型受体1(CELSR1)； 钙粘蛋白超家族CELSR1；
背景信息：
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008]
