基因名：
HDAC4
产品别名：
AHO3； BDMR； HA6116； HD4； HDAC-4； HDAC-A； HDACA； NEDCHF； NEDCHID； HDAC4； histone deacetylase 4； histone deacetylase 4； histone deacetylase 4； histone deacetylase A； 磷酸化组蛋白去乙酰化酶4； 磷酸化组蛋白去乙酰化酶4/5/7； 磷酸化组蛋白去乙酰化酶7； 组蛋白去乙酰化酶4； 组蛋白去乙酰化酶4+5+9； 组蛋白脱乙酰基酶4(HDAC4)；
背景信息：
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].
