基因名:
ELMO1
产品别名:
CED-12; CED12; ELMO-1; ELMO1; engulfment and cell motility 1; engulfment and cell motility 1; engulfment and cell motility protein 1; ced-12 homolog 1; 吞噬/细胞运动因子1(ELMO1); 吞噬细胞运动蛋白1;
背景信息:
ELMO1 is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. ELMO1 acts in association with DOCK1 and CRK and was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. It is belived to enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.