基因名：
USP15
产品别名：
UNPH-2； UNPH4； USP15； ubiquitin specific peptidase 15； ubiquitin specific peptidase 15； ubiquitin carboxyl-terminal hydrolase 15； deubiquitinating enzyme 15； ubiquitin thioesterase 15； ubiquitin thiolesterase 15； ubiquitin-specific-processing protease 15； 去泛素化酶15；
背景信息：
Usp15 belongs to a family of deubiquitinating enzymes called the DU subfamily. Within this subfamily are Usp4 and Usp11 because they all contain an N-terminal “domain present in ubiquitin specific proteases” (DUSP) and ubiquitin-like (UBL) domains. Usp15 has been shown to play a role in stabilizing and activating caspase-3 during Paclitaxel-induced apoptosis. Usp15 also deubiquitinates IκBα which is an inhibitor of NF-κB.
