重组甲状腺激素受体相关蛋白复合物230

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重组甲状腺激素受体相关蛋白复合物230

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant MED12
Recombinant mediator complex subunit 12 protein

基因名：

MED12

产品别名：

ARC240； CAGH45； FGS1； HDKR； HOPA； Kto； MED12S； OHDOX； OKS； OPA1； TNRC11； TRAP230； MED12； mediator complex subunit 12； mediator complex subunit 12； mediator of RNA polymerase II transcription subunit 12； CAG repeat protein 45； Kohtalo homolog； OPA-containing protein； activator-recruited cofactor 240 kDa component； human opposite paired； mediator of RNA polymerase II transcription, subunit 12 homolog； putative mediator subunit 12； thyroid hormone receptor-associated protein complex 230 kDa component； thyroid hormone receptor-associated protein, 230 kDa subunit； trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit)； trinucleotide repeat-containing gene 11 protein；甲状腺激素受体相关蛋白复合物230；

背景信息：

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009]

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。